Search results for "Halothane anaesthesia"

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ANTI-ARRHYTHMIC EFFECT OF DEHYDROBENZPERIDOL IN DOGS

1971

SUMMARY The anti-arrhythmic activity of dehydrobenzperidol (DBP) was studied during halothane anaesthesia in dogs. Arrhythmias were provoked by single intravenous injections of catecholamines. Two groups of dogs were studied. One received norepinephrine and the odier epinephrine. The dose just sufficient to initiate arrirythmias was defined as the “threshold”. Electrocardiogram, blood pressure and heart rate were monitored. The principal findings were:— 1  The dog heart was “sensitized” to epinephrine and norepinephrine by halothane. 2  DBP did have an anti-arrhydimic action. A dose of 0.150 mg/kg roughly doubled the “threshold”. 3  DBP had significant alpha-adrenergic blocking properties. …

Malemedicine.medical_specialtyEpinephrineBlood PressureNorepinephrine (medication)ElectrocardiographyNorepinephrineDogsHeart RateInternal medicineHeart ratemedicineAnimalsAnti arrhythmiccardiovascular diseasesbusiness.industryBenperidolRespirationHalothane anaesthesiaHeartGeneral MedicineDehydrobenzperidolAnesthesiology and Pain MedicineEndocrinologyEpinephrineFemaleDog heartHalothaneHalothanebusinesscirculatory and respiratory physiologymedicine.drugActa Anaesthesiologica Scandinavica
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Elimination of Parathion by Hemoperfusion in Severe E 605 ForteR Intoxication in Vivo

1978

Severe parathion (P) intoxication results in complete inhibition of cholinesterase activity and toxic accumulation of acetylcholine. Besides these well known biochemical changes, there is evidence of direct toxic effects on the cardio-vascular system which may prove fatal due to an excess of P.

biologymedicine.drug_classmedicine.medical_treatmentHalothane anaesthesiamacromolecular substancesPharmacologyHemoperfusionchemistry.chemical_compoundParathionchemistryIn vivobiology.proteinmedicineCarbonic anhydrase inhibitorAcetylcholineCholinesterasemedicine.drug
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